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Alexa Fluor® 488 Mouse Anti-Human CD66a/c/e Antibody (S-3923)

Alexa Fluor® 488 Mouse Anti-Human CD66a/c/e Antibody (S-3923)

Catalog Number: S0B80279 Application: FCM Reactivity: Hu Conjugation: Alexa Fluor® 488 Brand: Starter
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Product Details

Product Specification


Host Mouse
Antigen CD66a/c/e
Synonyms CEACAM1; BGP-1; BGP; BGP1; CEACAM6; NCA; CEACAM5; CEA
Location Cell membrane
Accession P13688、P40199、P06731
Clone Number S-3923
Antibody Type Mouse mAb
Isotype IgG2b,k
Application FCM
Reactivity Hu
Positive Sample human peripheral blood leukocytes
Purification Protein A
Concentration 0.1 mg/ml
Conjugation Alexa Fluor® 488
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.09% sodium azide
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 2 μl per million cells in 100μl volume Hu

Background

CD66a/c/e are closely related glycoproteins of the carcinoembryonic-antigen family that share an N-terminal IgV-like domain followed by up to three IgC2-like domains, differ mainly in membrane anchorage (CD66a is transmembrane whereas CD66c and CD66e are GPI-linked), and collectively mediate calcium-independent homophilic and heterophilic adhesion, pathogen recognition (e.g., gonococcal Opa proteins bind peptide determinants in their N-domains), neutrophil activation, and modulation of innate and adaptive immunity, apoptosis, angiogenesis, and tumor behavior.

Picture

FC

Flow cytometric analysis of CD66a/c/e expression on human peripheral blood leukocytes. Human peripheral blood leukocytes were stained with Alexa Fluor® 488 Mouse IgG2b, k Isotype Control (left panel) or SDT Alexa Fluor® 488 Mouse Anti-Human CD66a/c/e antibody (right panel) at 2 μl/test. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.