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Alexa Fluor® 488 Mouse Anti-Human CD138 Antibody (S-3450)

Alexa Fluor® 488 Mouse Anti-Human CD138 Antibody (S-3450)

Catalog Number: S0B80198 Application: FCM Reactivity: Hu Conjugation: Alexa Fluor® 488 Brand: Starter
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Regular price $150 USD
Regular price Sale price $150 USD
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Product Details

Product Specification


Host Mouse
Antigen CD138
Synonyms Syndecan-1; SYND1; SDC; SDC1
Location Membrane
Accession P18827
Clone Number S-3450
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Positive Sample U266B1
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 488
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD138, also known as syndecan-1, is a transmembrane heparan sulfate proteoglycan that plays a crucial role in cell adhesion, migration, and signaling. It is predominantly expressed on the surface of plasma cells and certain epithelial cells. In plasma cells, CD138 serves as a valuable marker for their identification and isolation, aiding in the diagnosis and study of plasma cell disorders such as multiple myomael. On epithelial cells, it contributes to the maintenance of cell structure and function by interacting with extracellular matrix components and growth factors. Additionally, CD138 is involved in various biological processes including wound healing, inflammation, and cancer progression. Its ability to bind and modulate the activity of numerous proteins makes it an important factor in cellular communication and regulation.

Picture

FC

Flow cytometric analysis of Jurkat (human T cell leukemia T lymphocyte, left) / U266B1 (human multiple myeloma B lymphocyte, right) labelling SDT Alexa Fluor® 488 Mouse Anti-Human CD138 Antibody at 5 μl/test (red) compared with Mouse IgG1, k Isotype Control (black). Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
Negative control: Jurkat