Human VEGFA Single Plex Kit (Flow Cytometry Bead Assay)

Vascular endothelial growth factor (VEGF) is a subfamily of growth factors that play a critical role in stimulating angiogenesis—the formation of new blood vessels. As a key signaling protein, VEGF is involved in both embryonic vascular development and the physiological or pathological growth of existing vasculature. The VEGF family comprises several members, including VEGF-A, VEGF-B, VEGF-C, VEGF-D, and placental growth factor (PlGF), with VEGF-A being the first identified. Prior to the discovery of other isoforms, VEGF-A was commonly referred to as VEGF. Due to its central role in promoting tumor angiogenesis, VEGF is essential for tumor development and metastasis, making it a pivotal target in cancer therapeutics. Accumulating evidence indicates that single nucleotide polymorphisms (SNPs) within the VEGF gene may serve as predictive and prognostic biomarkers for major solid tumors, such as breast cancer, non-small cell lung cancer, colorectal cancer, and prostate cancer.