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TPK1 His Tag Protein, Human

TPK1 His Tag Protein, Human

Catalog Number: UA010200 Reactivity: Human Conjugation: Unconjugated Brand: UA BIOSCIENCE
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Regular price $560 USD
Regular price Sale price $560 USD
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Product Details

Product Specification


Species Human
Synonyms TPK1, Thiamin pyrophosphokinase 1, hTPK1, Placental protein 20, PP20, Thiamine pyrophosphokinase 1
Accession Q9H3S4
Amino Acid Sequence Met1-Ser243, with C-8*His
Expression System E.coli
Molecular Weight 27-28kDa
Purity >95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1、Mayr J A. et al. (2011) Thiamine pyrophosphokinase deficiency in encephalopathic children with defects in the pyruvate oxidation pathway. Am J Hum Genet. 89(6): 806-812.

2、Bellyei S.et al. (2005) Cloning, sequencing, structural and molecular biological characterization of placental protein 20 (PP20)/human thiamin pyrophosphokinase (hTPK). Placenta. 26(1): 34-46.

Background

Thiamin pyrophosphokinase 1 (TPK1), a member of the thiamine pyrophosphokinase family, is also known as Thiamine pyrophosphokinase 1, Placental protein 20 (PP20) and hTPK1, which is detected in heart, kidney, testis, small intestine and peripheral blood leukocytes, and at very low levels in a variety of tissues. TPK1 is regarded as a Kinase and a Transferase that can bind ATP and Nucleotide.

Picture

SDS-PAGE

1μg (R: reducing condition, N: non-reducing condition).

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