PanModification Microspheres for PTM Proteomics

1. Concept

Posttranslational modifications (PTMs) diversify proteome functions and regulate nearly all cellular processes. Individual proteins may carry multiple PTMs with crosstalk between them. However, low abundance and high diversity hinder largescale analysis.

2. Research Frontier

Traditional PTM enrichment targets only one modification type. Panmodification microspheres integrate multiple probes on one carrier to simultaneously enrich phosphorylation, acetylation, ubiquitination, methylation and other common PTMs, enabling multidimensional proteomic analysis.

3. Research Significance

· Enables onestep enrichment of multiple PTMs, saving samples and improving efficiency.

· Enhances detection depth and discovers modification crosstalk.

· Facilitates identification of diseasespecific PTM signatures.

· Supports largecohort biomarker screening and quantitative proteomics.

4. Mechanism and Application

· Design principle: Covalently couple multiple PTMspecific probes onto microspheres.

· Advantages: High throughput, broad coverage, good reproducibility, low nonspecific binding.

· Applications: Signaling pathway analysis, disease mechanism study, biomarker discovery, drug evaluation.

· Product application: Antiacetyllysine agarose beads for efficient acetylation enrichment.

5. Brand Mission

ANT BIO PTE. LTD. is a professional life science reagent supplier focusing on antibodies, proteins, kits and general reagents. Our subbrands Absin (general reagents & kits), Starter (antibodies) and UA (recombinant proteins) provide innovative tools for PTM proteomics and translational research.

6. Related Product List

ANT BIO PTE. LTD. – Empowering Scientific Breakthroughs

At ANTBIO, we are committed to advancing life science research through highquality, reliable reagents and comprehensive solutions. Our specialized subbrands (Absin, Starter, UA) cover a full spectrum of research needs, from general reagents and kits to antibodies and recombinant proteins. With a focus on innovation, quality, and customercentricity, we strive to be your trusted partner in unlocking scientific mysteries and driving medical progress. Explore our product portfolio today and elevate your research to new heights.