InVivoPlus anti-mouse CD25

InVivoPlus anti-mouse CD25

 

Starter's Featured Product Recommendation: InVivoPlus anti-mouse CD25 (IL-2Rα)

I. Product Background
Targets of regulatory T cells and mechanisms of suppression.

IL-2Rα is the 55 kDa ligand-binding subunit of the interleukin 2 receptor α chain. IL-2Rα is expressed on activated mature T and B lymphocytes, thymocyte subsets, pre-B cells, and T regulatory cells. IL-2Rα has been shown to play a role in lymphocyte differentiation, activation, and proliferation. Alone, IL-2Rα binds IL-2 with relatively low affinity. However, when IL-2Rα combines with IL-2Rβ (CD122) and the common γ chain (CD132), the complex binds IL-2 with high affinity. The PC-61.5.3 antibody has been shown to inhibit IL-2 binding to both low and high affinity IL-2 receptors.

II. Application & Product Information

Product No. S0B0873
Product Name In vivo anti-mouse CD25 Recombinant mAb
Host Rat
Antigen Name CD25
Clone No. S-R441
Antibody Type Recombinant mAb
Antibody Isotype IgG2a, k
Isotype Control SOB0932
Applications In vivo regulatory T cell depletion, FCM
Purification Protein G
Concentration 5 mg/ml
Purity >95% Determined by SDS-PAGE
Endotoxin <2EU/mg

 

Catalog Number Product Name Species Expression System Conjugation Price
S0B0290 CD25/IL-2Rα Recombinant Rabbit mAb (S-R223) Rabbit Unconjugated Inquiry
S0C2015 CD25/IL-2Rα, FOXP3, CD4 Antibody Panel Unconjugated 400
S0B0704 CD25/IL-2Rα Recombinant Rabbit mAb (S-548-137) Rabbit Unconjugated Inquiry
S0B0921 Mouse Anti-Human CD25 Antibody (S-R494) Mouse Unconjugated Inquiry
S0B0959 Rat Anti-Mouse CD25 Antibody (S-R441) Rat Unconjugated Inquiry
S0B0559 Anti-CD254 Monoclonal Antibody(Denosumab) Human Unconjugated 1450
UA010675 Biotinylated IL-2R alpha/CD25 Fc&Avi Tag Protein, Human Human HEK293 Biotin 560
UA010367 IL-2R alpha/CD25 His Tag Protein, Human Human HEK293 Unconjugated 514
UA010324 IL-2R alpha/CD25 His Tag Protein, Mouse Mouse HEK293 Unconjugated 540
S0B1128 OX40L/TNFSF4/CD252 Recombinant Rabbit mAb (S-1337-18) Rabbit Unconjugated Inquiry
S0A6043 Human OX40L/TNFSF4/CD252, His tag Human HEK293 145
S0A1143 Human TNFSF13B/BAFF/CD257 Protein, hFc tag Human HEK293 Unconjugated Inquiry
S0A1142 Mouse IL-2R alpha/CD25 Protein, hFc tag Mouse HEK293 Unconjugated Inquiry
UA010260 IL-2R alpha/CD25 Fc Chimera Protein, Human Human HEK293 Unconjugated 514
S0B0873 Invivo anti-mouse CD25 Recombinant mAb Rat Unconjugated 150
S0B1545 Alexa Fluor® 647 Rat Anti-Mouse CD25 Antibody (S-R441) Rat Alexa Fluor® 647 110
S0B1781 Biotin Rat Anti-Mouse CD25 Antibody (S-R441) Rat Biotin 110
S0B5186 Alexa Fluor® 647 Mouse Anti-Rat CD25 Antibody (S-R676) Mouse Alexa Fluor® 647 75
S0B5207 Mouse Anti-Rat CD25 Antibody (S-R676) Mouse Unconjugated 100
S0B5215 FITC Rat Anti-Mouse CD25 Antibody (S-R441) Rat FITC 50
S0B5384 FITC Mouse Anti-Human CD25 Antibody (S-R494) Mouse FITC 150
S0B5335 Alexa Fluor® 647 Mouse Anti-Human CD25 Antibody (S-R494) Mouse Alexa Fluor® 647 330
S0B5266 Alexa Fluor® 488 Mouse Anti-Human CD25 Antibody (S-R494) Mouse Alexa Fluor® 488 340
S0B5437 FITC Mouse Anti-Rat CD25 Antibody (S-R676) Mouse FITC 100