InVivoMAb anti-mouse CD8α
03 Jun 2025
Starter's Featured Product Recommendation: InVivoMAb anti-mouse CD8α
I. Product Background
The CD8 antigen is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to class I MHC molecules presented by antigen - presenting cells (APCs). It is primarily found on the surface of cytotoxic T cells but is also expressed on thymocytes, natural killer cells, and some dendritic cell subsets. CD8 most commonly exists as a heterodimer composed of one CD8α and one CD8β chain, though it can also form a homodimer of two CD8α chains. Both the CD8α and CD8β chains exhibit significant homology to immunoglobulin variable light chains, with each chain having a molecular weight of approximately 34 kDa.
II. Application & Product Information
| Product No. | S0B0660 |
|---|---|
| Product Name | In vivo anti-mouse CD8α Recombinant mAb |
| Host | Rat |
| Synonyms | T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, Lyt-2, Lyt 2 |
| Cellular Location | Cell membrane |
| Clone No. | 2.43 |
| Antibody Type | Recombinant mAb |
| Antibody Isotype | Rat IgG2b, k |
| Applications | In vivo CD8+ T cell depletion, FCM, WB |
| Purification | Protein G |
| Concentration | Lot specific* (generally 5 to 10 mg/ml)* |
| Purity | >95% |
| Catalog Number | Product Name | Species | Conjugation | Price |
| S0B1555 | FITC Mouse Anti-Human CD8α Antibody (S-1036-34) | Mouse | FITC | 110 |
| S0B1141 | Invivo anti-Mouse CD8α Recombinant mAb | Rat | Unconjugated | 150 |
| S0B5219 | Alexa Fluor®488 Mouse Anti-Human CD8 Antibody(S-R533) | Mouse | Alexa Fluor® 488 | 135 |
| S0B5202 | FITC Mouse Anti-Rat CD86 Antibody (S-R580) | Mouse | FITC | 70 |
| S0B5208 | Mouse Anti-Rat CD86 Antibody (S-R580) | Mouse | Unconjugated | 100 |
| S0B5252 | Biotin Mouse Anti-Human CD8 Antibody (S-R533) | Mouse | Biotin | 25 |
| S0B5242 | Biotin Rat Anti-Mouse CD8α Antibody (S-R540) | Rat | Biotin | 20 |
| S0B5228 | Pacific Blue Mouse Anti-Human CD8 Antibody(S-R533) | Mouse | Pacific blue | 45 |
| S0B5166 | Alexa Fluor® 700 Rat anti-Mouse CD8α Antibody (S-R381) | Rat | Alexa Fluor® 700 | 95 |
| S0B5078 | PerCP-Cy5.5 Rat Anti-Mouse CD8a Antibody (S-R540) | Rat | PerCP-Cy5.5 | 50 |
