InVivoMAb anti-mouse IFNγ
28 May 2025
I. Product Background
Type I interferon controls innate and adaptive immunity and intracellular antimicrobial programmes.
Interferon γ (IFNγ) is a 20 kDa soluble pleiotropic cytokine and the only member of class II interferons. IFNγ is primarily produced by activated lymphocytes, including T cells, B cells, NK cells, and innate lymphoid cells (ILCs). It exerts immunoregulatory, antiproliferative, antiviral, and proinflammatory activities and plays an important role in the activation, growth, and differentiation of T and B lymphocytes, macrophages, NK cells, and other non-hematopoietic cell types. In addition, IFNγ induces the production of cytokines, Fc receptors, and adhesion molecules and upregulates the expression of MHC class II antigens on antigen-presenting cells during the immune response.
IFNγ has also been shown to regulate macrophage effector functions, influence isotype switching, and induce immunoglobulin secretion by B cells. IFNγ signals through the IFNγ receptor, a heterodimer composed of CD119 (IFNγ receptor 1) and AF-1 (IFNγ receptor 2). The IFNγ receptor is widely expressed in almost all cell types except for mature red blood cells.
II. Application & Product Information
| Product No. | S0B0956 |
|---|---|
| Product Name | In vivo anti-mouse IFNγ Recombinant mAb |
| Host | Rat |
| Antigen Name | Mouse IFNγ |
| Synonyms | Interferon gamma, IFN-gamma, Ifng |
| Clone No. | S-R489 |
| Antibody Type | Recombinant mAb |
| Antibody Isotype | Rat IgG1, k |
| Applications | In vivo IFNγ neutralization, in vitro IFNγ neutralization, WB |
| Purification | Protein G |
| Concentration | Lot specific* (generally 2 to 10 mg/ml)* |
| Endotoxin | <2EU/mg |
Product Information
|
Catalog Number
|
Product Name
|
Species
|
Price
|
|---|
|
IFN-γ Recombinant Rabbit mAb (SDT-212-36)
|
Rabbit
|
|
Unconjugated
|
|
$1,335
|
|
|
IFN-alpha1 Recombinant Rabbit mAb (SDT-095-40)
|
Rabbit
|
|
Unconjugated
|
|
$835
|
|
|
IFN-alpha1 Recombinant Rabbit mAb (SDT-095-163)
|
Rabbit
|
|
Unconjugated
|
|
$835
|
|
|
IFN-alpha Recombinant Rabbit mAb (SDT-095-39)
|
Rabbit
|
|
Unconjugated
|
|
$835
|
|
|
IFN-alpha Recombinant Rabbit mAb (SDT-095-142)
|
Rabbit
|
|
Unconjugated
|
|
$835
|
|
|
IL-28A/IFN-λ2 Recombinant Rabbit mAb (SDT-1616-14)
|
Rabbit
|
|
Unconjugated
|
|
Inquiry
|
|
|
IL-28B/IFN-λ3 Recombinant Rabbit mAb (SDT-1838-120)
|
Rabbit
|
|
Unconjugated
|
|
$1,250
|
|
|
IL-28B/IFN-λ3 Recombinant Rabbit mAb (SDT-1838-77-2)
|
Rabbit
|
|
Unconjugated
|
|
$1,250
|
|
|
IL-28B/IFN-λ3 Recombinant Rabbit mAb (SDT-1838-77)
|
Rabbit
|
|
Unconjugated
|
|
$1,250
|
|
|
Invivo anti-mouse IFNγ Recombinant mAb
|
Rat
|
|
Unconjugated
|
|
$150
|
