1μg (R: reducing condition, N:non-reducing condition).
TACI/CD267/TNFRSF13B His Tag Protein, Human
TACI/CD267/TNFRSF13B His Tag Protein, Human
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | CVID; CVID2; FLJ39942; MGC133214; ACIMGC39952; TNFRSF13B |
| Accession | O14836-1 |
| Amino Acid Sequence | Ser2-Thr166 with His Tag at the C-terminus |
| Expression System | HEK293 |
| Molecular Weight | 19-22kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE & RP-HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, PH7.4,5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | von Bulow, G.U. et al. (1997) Science, 278:138. |
Background
TACI (Transmembrane activator and CAML interactor) is a type III transmembrane protein and a member of the TNF receptor superfamily. It consists of an extracellular domain containing two cysteine-rich regions, a transmembrane domain, and an intracellular domain. TACI shares high homology with BCMA and binds to APRIL and BAFF, key ligands involved in immune regulation. Expressed on B cells and activated T cells, TACI plays a crucial role in B cell development and function. Its interactions with APRIL and BAFF suggest involvement in immune signaling pathways, making it a potential target for immunotherapy.
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SDS-PAGE
ELISA
Immobilized BAFF Protein, Human (Cat. No. UA040367) at 1.0μg/mL (100μL/well) can bind TACI/CD267/TNFRSF13B His Tag Protein, Human (Cat. No. UA011174) with EC50 of 2.07-3.92ng/mL.
