SCF Protein, Mouse

Catalog Number: UA040149 Brand: UA BIOSCIENCE

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$1,780 USD

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Product Details

Product Specification

Species	Mouse
Synonyms	KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, SHEP7, KL
Accession	P20826
Amino Acid Sequence	Lys26-Ala189
Expression System	E.coli
Molecular Weight	18kDa (Reducing)
Purity	＞95% by SDS-PAGE
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM Tris, 100mM NaCl, pH8.0
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1.Review Physiol Rev. 2012 Oct;92(4):1619-49.

Background

Stem Cell Factor is also known as SCF,kit-ligand, KL, steel factor, KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, or SHEP7,and is a cytokine that binds to the c-Kit receptor (CD117). Stem cell factorsperform their biological functions by binding to and activating the receptortyrosine kinase c-Kit. The human SCF gene encodes for a 273 amino acidtransmembrane protein, which contains a 25 amino acid N-terminal signalsequence, a 189 amino acid extracellular domain, a 23 amino acid transmembranedomain, and a 36 amino acid cytoplasmic domain. Stem cell factor (SCF) has beenshown to stimulate the proliferation of myeloid, erythroid, and lymphoidprogenitor cells in bone marrow culture and has been shown to work synergicallywith colony-stimulating factors.