Premium(G3) Anti-L-lactyllysine agarose Beads
Premium(G3) Anti-L-lactyllysine agarose Beads
Product Details
Product Details
Product Specification
| Synonyms | L-Kla，Kla，L‑乳酸化，L-乳酰化 |
| Antibody Type | Recombinant mAb Mix |
| Isotype | IgG |
| Reactivity | Species Independent |
| Purification | Protein A |
| Physical Appearance | Liquid |
| Storage Buffer | 50% slurry in PBS pH7.4, 0.05% Proclin 300. Ensure thorough mixing before each use. Wide-mouth pipette tips are recommended. In case of difficulty in aspiration due to improper operation, additional Storage Buffer can be added at your discretion. |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Background
Lysine lactylation is an emerging post-translational modification that occurs in cellular metabolism, specifically referring to the accumulation of lactic acid modifying lysine residues on histones. Lysine lactylation modifies the chromatin structure, thereby affecting gene expression. Research has found that lactylation sites are widely distributed in gene promoter regions, closely associated with gene transcriptional activation. Lysine lactylation also participates in energy metabolism processes, potentially related to the dynamic balance regulation of histone lysine acetylation.
