• NOTCH2 Fc Chimera Protein, Human
1 1

NOTCH2 Fc Chimera Protein, Human

NOTCH2 Fc Chimera Protein, Human

Catalog Number: UA010861 Reactivity: Human Conjugation: Unconjugated Brand: UA BIOSCIENCE
Share:
Price:
$268 USD
$268 USD
Size:

For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details

Product Details

Product Specification


Species Human
Synonyms NOTCH2, hN2, N2ECD
Accession Q04721
Amino Acid Sequence Leu26-Gln530, with C-terminal hIgG1 Fc
Expression System HEK293
Molecular Weight 85-93kDa (Reducing)
Purity ＞95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4.
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.Gene ID: 4853, updated on 12-Dec-2023.

Background

Human Notch-2 is a 300 kDa type I transmembrane glycoprotein. Members of this Type 1 transmembrane protein family share structural characteristics and play a role in a variety of developmental processes by controlling cell fate decisions. As a receptor for the membrane-binding ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1), the ligands, activated by the released notch intracellular domain (NICD), form a transcription activator complex with RBPJ/RBPSUH to activate the division site enhancer gene.

Picture

SDS-PAGE

1μg (R: reducing condition, N: non-reducing condition).

SEC-HPLC