1μg (R: reducing condition, N: non-reducing condition).
MMP-9 His Tag Protein, Mouse
MMP-9 His Tag Protein, Mouse
Price:
Regular price
$456.00 USD
Regular price
Sale price
$456.00 USD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Species | Mouse |
| Synonyms | MMP9, CLG4B, GELB, MANDP2, Gelatinase B |
| Accession | P41245 |
| Amino Acid Sequence | Ala20-Pro730 with His Tag at C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 80-95kDa (Reducing) |
| Purity | > 95% by SDS-PAGE & SEC-HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
Background
Matrix metalloproteinase 9 (MMP-9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase, gelatinase B (GELB), or CLG4B, is secreted by neutrophils, macrophages, and various transformed cells. It is the most complex member of the MMP family in terms of domain structure and activity regulation.
Structurally, MMP-9 can be divided into five distinct domains: a prodomain that is cleaved upon activation, a gelatin-binding domain consisting of three contiguous fibronectin type II units, a catalytic domain with the zinc-binding site, a proline-rich linker region, and a carboxyl-terminal hemopexin-like domain. This enzyme degrades various substrates, including gelatin, collagen types IV and V, and elastin.
MMP-9 is implicated in a variety of autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis, and is considered a potential therapeutic target
Picture
Picture
SDS-PAGE
SEC-HPLC
The purity of MMP-9 His Tag Protein, Mouse is more than 95 % as determined by SEC-HPLC.
