IFN-γ Protein, Human
IFN-γ Protein, Human
Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | Immune Interferon,type II interferon,T cell interferon,MAF |
| Accession | P01579 |
| Amino Acid Sequence | Gln2-Gln166 with an N-terminal Met |
| Expression System | E.coli |
| Molecular Weight | Approximately 16.9 kDa, a single non-glycosylated polypeptide chain containing 144 amino acids. |
| Purity | ＞98% by SDS-PAGE or HPLC. |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS, with 5% (v/v) Trehalose, pH 7.4. |
| Reconstitution |
Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
| Stability & Storage | For long term storage, the product should be stored ≤ -20℃. |
Background
Interferon-gamma (IFN-γ) , also known as Type II interferon or immune interferon, is a dimerized soluble cytokine that is critical for innate and adaptive immunity against viral, some bacterial and protozoal infections. It is produced primarily by CD4 and CD8 T lymphocytes as well as natural killer (NK) and natural killer T (NKT) cells. The primary role for IFN-γ is the activation of macrophages to increase phagocytosis, tumoricidal properties, and intracellular killing of pathogens. IFN-γ also increases expression of MHC antigens by macrophages and this facilitates antigen presentation to T cells. The recombinant Interferon-gamma s a 16.9kDa protein consisting of 144 amino acid.
