The purity of DLK1/FA1 His Tag Protein, Cynomolgus is more than 95% determined by SEC-HPLC.
DLK1/FA1 His Tag Protein, Cynomolgus
DLK1/FA1 His Tag Protein, Cynomolgus
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Product Details
Product Details
Product Specification
| Species | Cynomolgus |
| Synonyms | Protein delta homolog 1, Pg2, Fetal antigen 1 |
| Accession | A0A2K5TMQ6-1 |
| Amino Acid Sequence | Ala24-Cys306 with His Tag at the C-terminus |
| Expression System | HEK293 |
| Molecular Weight | 33-45kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE & SEC-HPLC |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | Sheng J, Wu D, Shang J, Fu X, Gao H, Rong J, Wang J, Hu J, Qi X. Usp11 maintained the survival of marginal zone B cells under ionizing radiation by deubiquitinating DLL1 and JAG2. Cell Death Dis. 2025 Feb 4;16(1):67. |
Background
DLK-1, also known as preadipocyte factor 1 (Pref-1), is a transmembrane-secreted protein containing an epidermal growth factor (EGF)-like repeat sequence. It is expressed on the cell surface in various cancers, including hepatocellular carcinoma, and may serve as a potential target for monoclonal antibody therapy. DLK-1 regulates the growth of pioneer axons by modulating Wnt signaling. While primarily expressed as a transmembrane protein, a soluble form generated by ADAM17-mediated cleavage is active in inhibiting adipogenesis, the process by which pre-adipocytes differentiate into adipocytes.
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SDS-PAGE
SEC-HPLC
