Betacellulin Protein, Human
Betacellulin Protein, Human
Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | Betacellulin,BTC |
| Accession | P35070 |
| Amino Acid Sequence | Asp32-Tyr111 |
| Expression System | E.coli |
| Molecular Weight | 12-16kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage |
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Yamamoto K. et al. (2000) Recombinant human betacellulin promotes the neogenesis ofβ-Cells and ameliorates glucose intolerance in mice with diabetes induced by selective alloxan perfusion. Diabetes. 49(12): 2021-2027. |
Background
Betacellulin (BTC) is a member of the epidermal growth factor (EGF) family. Betacelluli is expressed in most tissues including kidney, uterus, liver and pancreas. It is also present in body fluids, including serum, milk, and colostrum. It is synthesized primarily as a transmembrane precursor, which is then processed to a mature molecule by proteolytic events. Betacellulin signals through the EGF receptor.
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SDS-PAGE
