Immobilized Human PRL Protein, His Tag at 1.0 μg/mL (100μL/well) can bind Prolactin R/PRLR Fc Chimera Protein, Human (Cat. No. UA016068) with EC50 of 4.7-6.3 ng/mL.
Human PRL Protein, His Tag
Human PRL Protein, His Tag
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | Prolactin, Lactotropin |
| Accession | P01236 |
| Amino Acid Sequence | Protein sequence (P01236, Leu29-Cys227, with C-His Tag) LPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFDKRYTHGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYHLVTEVRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHPETKENEIYPVWSGLPSLQMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNNNC |
| Expression System | HEK293 |
| Molecular Weight | Predicted MW: 24.6 kDaObserved MW: 25, 28 kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4 with 3% trehalose. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
Prolactin (PRL), also known as lactotropin, is a protein best known for its role in enabling mammals to produce milk. Prolactin is secreted from the pituitary gland in response to eating, mating, estrogen treatment, ovulation and nursing. It is secreted heavily in pulses in between these events. Prolactin plays an essential role in metabolism, regulation of the immune system and pancreatic development. Prolactin levels may be checked as part of a sex hormone workup, as elevated prolactin secretion can suppress the secretion of follicle stimulating hormone and gonadotropin-releasing hormone, leading to hypogonadism and sometimes causing erectile dysfunction. Prolactin levels may be of some use in distinguishing epileptic seizures from psychogenic non-epileptic seizures. The serum prolactin level usually rises following an epileptic seizure.
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Bioactivity
SDS-PAGE
2μg（R: reducing conditions）
