Immobilized PD-1 His Tag Protein, Human(UA010004) can bind Pembrolizumab. The EC50 for this effect is 13.74 ng/mL.
Anti-PD-1 Monoclonal Antibody (Pembrolizumab)
Anti-PD-1 Monoclonal Antibody (Pembrolizumab)
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$325 USD
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Product Details
Product Details
Product Specification
| Host | Human |
| Antigen | PD-1 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG4,k |
| Application | Blocking of PD-1/PD-L1 signaling Functional assays |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative.Endotoxin level is ≤ 1 EU/mg |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Background
Pembrolizumab is a humanized monoclonal IgG4 kappa antibody directed against human cell surface PD-1 (programmed death receptor-1) on lymphocytes. The PD-1 receptor provides an important “immune checkpoint,” which helps prevent the immune system from attacking itself.
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Validation Data
