Immobilized IL-4R alpha/CD124 His Tag Protein, Human(UA010382) can bind Dupilumab. The EC50 for this effect is 63.35 ng/mL.
Anti-CD124 Monoclonal Antibody(Dupilumab)
Anti-CD124 Monoclonal Antibody(Dupilumab)
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$300 USD
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$300 USD
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Product Details
Product Details
Product Specification
| Host | Human |
| Synonyms | Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, CD124 |
| Accession | P24394 |
| Clone Number | S-SC022 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG4,k |
| Application | Blocking of IL-4Rα signaling Functional assays |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| ELISA | 1.221-5000 ng/ml |
Background
Dupilumab is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis.
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ELISA
