| Host | Rabbit |
| Antigen | CLDN7 |
| Synonyms | CEPTRL2, CPETRL2, Claudin-7, Claudin 7 |
| Immunogen | Synthetic Peptide |
| Location | Intracellular |
| Accession | O95471 |
| Clone Number | SDT-077-17 |
| Antibody Type | Rabbit mAb |
| Application | IHC-P |
| Reactivity | Hu, Ms |
| Purification | Protein A |
| Concentration | 0.5mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
| application | dilution | species |
| IHC-P | 1:2000 |
Claudin is a transmembrane protein with four transmembrane domains. Claudin-7 (Cldn7) is a member of the claudin family, and its basic function is to maintain cell polarity and form tight junctions. CLDN7 has a full-length form (211 amino acids) and a C-terminal truncated form (158 amino acids). Recent studies have shown that low expression of the Cldn7 protein is found in a variety of malignant tumors, such as lung cancer, breast cancer, pancreatic cancer, and colorectal cancer (CRC).
IHC shows positive staining in paraffin-embedded human colon cancer
.Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.
Counterstained with hematoxylin.
Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human endometrial cancer.
Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.
Counterstained with hematoxylin.
Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human breast cancer.
Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.
Counterstained with hematoxylin.
Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human colon.
Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.
Counterstained with hematoxylin.
Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded mouse colon.
Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.
Counterstained with hematoxylin.
Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows negative staining in paraffin-embedded human renal clear cell carcinoma.
Anti-CLDN7 antibody was used at 1/2000 dilution, followed by a Goat Anti-Rabbit IgG H&L (HRP) ready to use.
Counterstained with hematoxylin.
Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
