Product Details
Product Details
Product Specification
Description |
Detection Principle: Detection Type: Double antibody sandwich method Form: pre coated 96 well plate Test Sample Type: cell supernatant, serum, plasma Loading Amount: 100 μ L Kit Components: Pre coated 96 well plates, standards, il-1α One copy of detection antibody, standard dilution, detection buffer, TMB chromogenic substrate, washing solution, termination solution, sa-hrp, plate sealing membrane and instructions. Sensitivity: 0.52pg/ml Detection Range: 7.81-500 pg/ml Recovery Range: 81-106% Storage Method: 2-8 ℃ Standard Curve: Background: Interleukin 1 (IL-1)It is a 17kDa extracellular polypeptide, which is divided into il-1α And il-1β Both proteins. Il-1α Is a pleiotropic cytokine encoded by the IL1A gene in humans. Il-1α It is mainly produced by activated macrophages, neutrophils, epithelial cells and endothelial cells. It has metabolic, physiological and hematopoietic activities and plays a central role in regulating the immune response. IL-1α It can interact with HAX1 and NDN, but the synergy with TNF is the most clinically relevant. Il-1α And TNF are both acute phase cytokines with Pro febrile and inflammatory effects. At present, relevant scholars are evaluating il-1α Whether it can be used as a potential tumor treatment marker in clinical trials. Blocking il-1α Activity has potential therapeutic effects on skin diseases, such as acne. |
