Product Details
Product Details
Product Specification
Host | Rabbit |
Antigen | Free PSA |
Synonyms | fPSA, F-PSA |
Accession | P55786 |
Clone Number | SDT-195-317 |
Antibody Type | Recombinant mAb |
Isotype | IgG |
Application | CLIA, Sandwich ELISA |
Reactivity | Hu |
Cross Reactivity | Does not recognize PSA conplex, only recognize free PSA |
Purification | Protein A |
Concentration | 2mg/ml |
Purity | >95% by HPLC |
Conjugation | Unconjugated |
Physical Appearance | Liquid |
Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
application | dilution | species |
Sandwich ELISA | N/A |
Background
Prostate-specific antigen (PSA; also known as human kallikrein-related peptidase 3), a 237-amino-acid glycoprotein (33 kDa) that belongs to the kallikrein serine protease family, is produced by the glandular epithelium of the human prostate and secreted in seminal fluid. PSA plays a principal role in the proteolysis of semenogelins I and II from seminal coagulum. Prostate-specific antigen (PSA) is a serum marker that is widely used for the diagnosis of prostatic diseases. Measurement of the free fraction of total prostate-specific antigen (fPSA%) has been proposed as a useful addition to total PSA for the detection of prostate cancer.
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