Anti-human TL1A Monoclonal Antibody (Tulisokibart)

Catalog Number: S0E0020 Application: Blocking of TL1A signaling Functional assays Reactivity: Hu Conjugation: Unconjugated Brand: Starter

Price:

$445 USD

Size: 1mg

Quantity:

For shipping services or bulk orders, you may request a quotation.

Secure checkout with

View full details

Product Details

Product Specification

Clone Number	S-SC042
Antibody Type	Recombinant mAb
Application	Blocking of TL1A signaling Functional assays
Reactivity	Hu
Purification	Protein A
Concentration	5 mg/ml
Endotoxin	<1EU/mg
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS pH7.4, containing no preservative
Stability & Storage	2 to 8 °C for 2 weeks under sterile conditions; -20 °C for 3 months under sterile conditions; -80 °C for 24 months under sterile conditions. Please avoid repeated freeze-thaw cycles.

Background

Tulisokibart is a humanized monoclonal antibody targeting Tumor Necrosis Factor-Like Cytokine 1A (TL1A), currently in clinical development, primarily for the treatment of moderate to severe active ulcerative colitis. It works by binding with high affinity and specificity to the TL1A protein, inhibiting its interaction with the DR3 receptor, thereby suppressing pro-inflammatory and pro-fibrotic pathways to achieve therapeutic effects in inflammatory bowel disease.