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Virus-Like Particle (VLP) Protein-isotype control

Virus-Like Particle (VLP) Protein-isotype control

Catalog Number: UA060024 Brand: UA BIOSCIENCE
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Regular price $158 USD
Regular price Sale price $158 USD
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Product Details

Product Specification


Species HIV
Synonyms VLP,Virus Like Particle,eVLP,VLPs
Concentration 0.27mg/ml by BCA
Expression System HEK293
Molecular Weight

kDa&kDa

Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 5% trehalose, PH7.4

Stability & Storage

·6 months from date of receipt, -60 to -80 °C as supplied.
·about 3 days in 2 to 8 °C.
·Please avoid repeated freeze-thaw cycles.

Reference

Belghith AA, Cotter CA, Ignacio MA, Earl PL, Hills RA, Howarth MR, Yee DS, Brenchley JM, Moss B. Mpox multiprotein virus-like nanoparticle vaccine induces neutralizing and protective antibodies in mice and non-human primates. Nat Commun. 2025 May 21;16(1):4726.

Background

Virus-like particles (VLPs) are highly structured protein particles composed of single or multiple structural proteins of the virus. Its morphological structure is similar to that of natural virus particles, does not contain virus accounting, and has strong immunogenicity and biological activity. The empty shell structure of most VLP is icosahedral or helical structure, which is composed of several specific structural proteins. At present, it is widely used in vaccine production and antigen presentation.

Picture

SDS-PAGE

1μg (R: reducing condition).

ELISA

Immobilized p55 Gag-VLP at 5.0μg/mL (100μL/well) can bind Anti-HIV1 p24 antibody with EC50 of 31.57-42.51ng/mL.

DLS

The mean peak Radius of VLP is 120-180 nm with more than 95% intensity as determined by dynamic light scattering (DLS)

Electron Microscope

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