Product Details
Product Details
Product Specification
Host | Rabbit |
Antigen | Adiponectin |
Synonyms | Acrp30 |
Immunogen | Recombinant Protein |
Accession | Q15848 |
Clone Number | SDT-692-98 |
Antibody Type | Recombinant mAb |
Isotype | IgG |
Application | Sandwich ELISA |
Reactivity | Hu |
Cross Reactivity | Does not recognize C1qTNF9 |
Purification | Protein A |
Concentration | 2 mg/ml |
Purity | >95% by HPLC |
Conjugation | Unconjugated |
Physical Appearance | Liquid |
Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
application | dilution | species |
Sandwich ELISA | N/A |
Background
Adiponectin (also referred to as AdipoQ and Acrp30) is a 30 kDa protein hormone and adipokine that is secreted primarily by adipocytes. Plasma levels of adiponectin at around 2-30 μg/mL. Mature human Adiponectin consists of a 60 amino acid (aa) N-terminal collagenous region and a 137 aa C-terminal C1q/TNF-a-like globular domain. Adiponectin forms 90 kDa homotrimers that contain two disulfide-linked monomers and a third subunit which is noncovalently associated. Two trimers can be covalently linked to create a 180 kDa hexamer which associates into >300 kDa high molecular weight (HMW) Adiponectin. Adiponectin modulates several metabolic processes, including glucose regulation and fatty acid oxidation.
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