Targeting NF-κB p65 DNA-Binding Activity: Can Sesquiterpene Lactones’ α-M-γ-B Core Improve Arthritis?

Targeting NF-κB p65 DNA-Binding Activity: Can Sesquiterpene Lactones’ α-M-γ-B...

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  1. Concept of NF-κB p65 and Rheumatoid Arthritis Pathogenesis Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic synovitis, pannus formation, and progressive bone/cartilage destruction. Its pathology is...

29 Jan 2026AntBio

Targeting NF-κB p65 DNA-Binding Activity: Can Sesquiterpene Lactones’ α-M-γ-B...

  1. Concept of NF-κB p65 and Rheumatoid Arthritis Pathogenesis Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic synovitis, pannus formation, and progressive bone/cartilage destruction. Its pathology is...

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NF-κB Signaling Pathway: Generation and Regulatory Mechanisms of p105/p50

NF-κB Signaling Pathway: Generation and Regulatory Mechanisms of p105/p50

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  1. Concept of NF-κB Pathway and Its Biological Significance The nuclear factor-kappa B (NF-κB) signaling pathway is a highly conserved transcriptional regulatory network, serving as a central hub for...

29 Jan 2026AntBio

NF-κB Signaling Pathway: Generation and Regulatory Mechanisms of p105/p50

  1. Concept of NF-κB Pathway and Its Biological Significance The nuclear factor-kappa B (NF-κB) signaling pathway is a highly conserved transcriptional regulatory network, serving as a central hub for...

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LECT2: A Liver-Secreted Factor Regulating Renal Fibrosis via Endoplasmic Reticulum Stress and EGFR Signaling

LECT2: A Liver-Secreted Factor Regulating Renal Fibrosis via Endoplasmic Reti...

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  1. Concept of LECT2 and Renal Fibrosis Renal fibrosis is a common pathological endpoint of chronic kidney diseases, characterized by persistent inflammation, myofibroblast activation, and excessive extracellular matrix deposition....

29 Jan 2026AntBio

LECT2: A Liver-Secreted Factor Regulating Renal Fibrosis via Endoplasmic Reti...

  1. Concept of LECT2 and Renal Fibrosis Renal fibrosis is a common pathological endpoint of chronic kidney diseases, characterized by persistent inflammation, myofibroblast activation, and excessive extracellular matrix deposition....

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Immune Checkpoint Antibodies: The Cornerstone Raw Materials of Tumor Immunotherapy

Immune Checkpoint Antibodies: The Cornerstone Raw Materials of Tumor Immunoth...

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1. Concept of Immune Checkpoints and T Cell Immune Regulation Immune checkpoints are a class of signal-regulating molecules expressed on T cells, antigen-presenting cells, and other immune cells, serving as...

29 Jan 2026AntBio

Immune Checkpoint Antibodies: The Cornerstone Raw Materials of Tumor Immunoth...

1. Concept of Immune Checkpoints and T Cell Immune Regulation Immune checkpoints are a class of signal-regulating molecules expressed on T cells, antigen-presenting cells, and other immune cells, serving as...

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Transforming Growth Factor Beta (TGF-β): Unraveling Its Dual Roles in Cell Fate and Disease Progression

Transforming Growth Factor Beta (TGF-β): Unraveling Its Dual Roles in Cell Fa...

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  1. Concept of TGF-β and Its Signaling Mechanisms Transforming Growth Factor Beta (TGF-β) is an evolutionarily conserved family of multifunctional secreted cytokines, playing pivotal roles in regulating cell biology...

29 Jan 2026AntBio

Transforming Growth Factor Beta (TGF-β): Unraveling Its Dual Roles in Cell Fa...

  1. Concept of TGF-β and Its Signaling Mechanisms Transforming Growth Factor Beta (TGF-β) is an evolutionarily conserved family of multifunctional secreted cytokines, playing pivotal roles in regulating cell biology...

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Plasma p-tau231: A Precise Early Biomarker for Alzheimer's Disease?

Plasma p-tau231: A Precise Early Biomarker for Alzheimer's Disease?

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1. Concept of Alzheimer's Disease and the Need for Early Biomarkers Alzheimer's disease (AD) is a neurodegenerative disorder characterized by neuropathological changes that manifest decades before clinical symptoms (e.g., memory...

29 Jan 2026AntBio

Plasma p-tau231: A Precise Early Biomarker for Alzheimer's Disease?

1. Concept of Alzheimer's Disease and the Need for Early Biomarkers Alzheimer's disease (AD) is a neurodegenerative disorder characterized by neuropathological changes that manifest decades before clinical symptoms (e.g., memory...

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