Recent Articles
How Atypical PKCζ Regulates Path...
Roles of Serine/Threonine Phosph...
Histone Crotonylation: Reshaping...
Lactylation: A Key Driver of Tumor Immune Evasion
Concept Lactylation is a histone and nonhistone lysine acylation modification where lactate-derived lactyl groups are covalently attached to proteins. Discovered in 2019, it links glycolytic metabolism to epigenetic regulation. In the...
Lactylation: A Key Driver of Tumor Immune Evasion
Concept Lactylation is a histone and nonhistone lysine acylation modification where lactate-derived lactyl groups are covalently attached to proteins. Discovered in 2019, it links glycolytic metabolism to epigenetic regulation. In the...
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Fumaroylation: A New Hub Linking Metabolism and Epigenetic Regulation
Concept Fumaroylation is a dynamic lysine acylation modification where a fumarate group is covalently attached to protein lysine residues. As a metabolite-driven epigenetic mark derived from the tricarboxylic acid (TCA) cycle...
Fumaroylation: A New Hub Linking Metabolism and Epigenetic Regulation
Concept Fumaroylation is a dynamic lysine acylation modification where a fumarate group is covalently attached to protein lysine residues. As a metabolite-driven epigenetic mark derived from the tricarboxylic acid (TCA) cycle...
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Methacrylation: Advances in Specific Chemical Labeling and Research Tools
Concept Methacrylation is a recently discovered protein lysine acylation modification, a structural isomer of crotonylation. It arises from methacrylyl-CoA and regulates chromatin function, metabolism, and disease-related pathways. Specific chemical labeling via photocatalytic...
Methacrylation: Advances in Specific Chemical Labeling and Research Tools
Concept Methacrylation is a recently discovered protein lysine acylation modification, a structural isomer of crotonylation. It arises from methacrylyl-CoA and regulates chromatin function, metabolism, and disease-related pathways. Specific chemical labeling via photocatalytic...
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Tryptic Peptide Mapping: A Cornerstone Tool for Biopharmaceutical Characteriz...
Concept Tryptic peptide mapping is a gold-standard analytical workflow that uses trypsin—a highly specific serine protease—to cleave proteins at the C-termini of arginine and lysine residues. The resulting peptides (6–25 amino...
Tryptic Peptide Mapping: A Cornerstone Tool for Biopharmaceutical Characteriz...
Concept Tryptic peptide mapping is a gold-standard analytical workflow that uses trypsin—a highly specific serine protease—to cleave proteins at the C-termini of arginine and lysine residues. The resulting peptides (6–25 amino...
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Phosphorylation Modification: The Molecular Switch Governing Life Activities
Concept Phosphorylation is a reversible, ubiquitous post-translational modification (PTM) where a phosphate group from ATP is transferred to serine, threonine, or tyrosine residues of a protein, catalyzed by kinases and reversed by...
Phosphorylation Modification: The Molecular Switch Governing Life Activities
Concept Phosphorylation is a reversible, ubiquitous post-translational modification (PTM) where a phosphate group from ATP is transferred to serine, threonine, or tyrosine residues of a protein, catalyzed by kinases and reversed by...
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Recombinant Rabbit Monoclonal Antibodies: Redefining Precision and Reliabilit...
Concept Recombinant rabbit monoclonal antibodies (rRb mAbs) are next-generation detection reagents that combine the unique immunological advantages of rabbits with modern genetic engineering. By cloning defined antibody genes and expressing...
Recombinant Rabbit Monoclonal Antibodies: Redefining Precision and Reliabilit...
Concept Recombinant rabbit monoclonal antibodies (rRb mAbs) are next-generation detection reagents that combine the unique immunological advantages of rabbits with modern genetic engineering. By cloning defined antibody genes and expressing...
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