Recent Articles

Can VEGFR Antibodies Become a New Strategy for Osteoarthritis?

Can VEGFR Antibodies Become a Ne...

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14 Oct 2026

Can VEGFR Antibodies Become a Ne...

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Th1/Th2 Subset Differentiation: From Cytokine Profiles to Metabolic Reprogramming

Th1/Th2 Subset Differentiation: ...

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14 Oct 2026

Th1/Th2 Subset Differentiation: ...

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Paired Antibodies for Progesterone: Three Pitfalls of a 314 Da Competitive Immunoassay

Paired Antibodies for Progestero...

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14 Oct 2026

Paired Antibodies for Progestero...

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mTOR (Ser2448) Phosphorylation: Decoding Central Regulatory Nodes Within mTOR‑Mediated Signalling Networks

mTOR (Ser2448) Phosphorylation: Decoding Central Regulatory Nodes Within mTOR...

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This cell‑metabolism signalling review explains mTORC1‑mTORC2 complex structural‑functional divergence, Ser2448 phosphorylation as mTORC1 activity read‑out, PI3K‑Akt‑AMPK upstream control and S6K1‑IRS1 negative‑feedback circuits. It features Phospho‑mTOR (Ser2448) recombinant rabbit mAb (S0B0597)...

20 Aug 2026AntBio

mTOR (Ser2448) Phosphorylation: Decoding Central Regulatory Nodes Within mTOR...

This cell‑metabolism signalling review explains mTORC1‑mTORC2 complex structural‑functional divergence, Ser2448 phosphorylation as mTORC1 activity read‑out, PI3K‑Akt‑AMPK upstream control and S6K1‑IRS1 negative‑feedback circuits. It features Phospho‑mTOR (Ser2448) recombinant rabbit mAb (S0B0597)...

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LATS1/2 Kinase (Ser909/872): Dual‑Function Regulator Balancing Intestinal Stem‑Cell Fate and Wnt‑Pathway Output

LATS1/2 Kinase (Ser909/872): Dual‑Function Regulator Balancing Intestinal Ste...

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This stem‑cell‑signalling review interprets dual‑mode regulatory functions of Hippo‑LATS1/2 kinase (Ser909/Ser872 phosphorylation) in intestinal‑stem‑cell homeostasis, YAP‑TAZ‑TLE‑TCF Wnt‑suppression, TEAD‑driven crypt‑proliferation, and Apc‑mutant intestinal tumour pre‑clinical‑model findings. It presents Phospho‑LATS1/2 (Ser909/872) recombinant...

20 Aug 2026AntBio

LATS1/2 Kinase (Ser909/872): Dual‑Function Regulator Balancing Intestinal Ste...

This stem‑cell‑signalling review interprets dual‑mode regulatory functions of Hippo‑LATS1/2 kinase (Ser909/Ser872 phosphorylation) in intestinal‑stem‑cell homeostasis, YAP‑TAZ‑TLE‑TCF Wnt‑suppression, TEAD‑driven crypt‑proliferation, and Apc‑mutant intestinal tumour pre‑clinical‑model findings. It presents Phospho‑LATS1/2 (Ser909/872) recombinant...

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Custom IP‑Grade Antibodies: Precision Research Tools for Capturing Native Target‑Protein Complexes

Custom IP‑Grade Antibodies: Precision Research Tools for Capturing Native Tar...

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This molecular‑biology technical review explains custom IP‑grade antibody development workflows, immunogen‑design principles, multi‑tiered functional‑validation criteria including KD affinity metrics, knockout‑cell‑based specificity testing, native‑complex capture and Co‑IP‑MS experimental‑considerations. It introduces custom...

19 Aug 2026AntBio

Custom IP‑Grade Antibodies: Precision Research Tools for Capturing Native Tar...

This molecular‑biology technical review explains custom IP‑grade antibody development workflows, immunogen‑design principles, multi‑tiered functional‑validation criteria including KD affinity metrics, knockout‑cell‑based specificity testing, native‑complex capture and Co‑IP‑MS experimental‑considerations. It introduces custom...

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Acetylation as a Molecular Switch Governing Tumour‑Suppressor p53 Functional Activity

Acetylation as a Molecular Switch Governing Tumour‑Suppressor p53 Functional ...

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This cancer‑epigenetics review covers p53 C‑terminal‑domain acetylation “de‑repression” regulatory mechanism, SET acidic‑domain non‑acetylated‑lysine reader function, p53 acetylation‑mimetic knock‑in mouse phenotypes, charge‑dependent protein‑protein‑interaction principles. It supplies pan‑acetyllysine antibody and anti‑acetyllysine agarose...

19 Aug 2026AntBio

Acetylation as a Molecular Switch Governing Tumour‑Suppressor p53 Functional ...

This cancer‑epigenetics review covers p53 C‑terminal‑domain acetylation “de‑repression” regulatory mechanism, SET acidic‑domain non‑acetylated‑lysine reader function, p53 acetylation‑mimetic knock‑in mouse phenotypes, charge‑dependent protein‑protein‑interaction principles. It supplies pan‑acetyllysine antibody and anti‑acetyllysine agarose...

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Ubiquitination: A Core Regulatory Hub Mediating Crosstalk Between Tumour Microenvironment and mTORC1 Signalling

Ubiquitination: A Core Regulatory Hub Mediating Crosstalk Between Tumour Micr...

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This tumour‑metabolism review interprets Rheb K8 ubiquitination as a molecular switch linking tumour‑microenvironment growth‑factor cues to mTORC1 signalling, RNF152‑USP4 regulatory axis, cell‑line‑xenograft‑AOM‑DSS in‑vivo experimental outputs and targeted‑small‑molecule research prospects. It...

19 Aug 2026AntBio

Ubiquitination: A Core Regulatory Hub Mediating Crosstalk Between Tumour Micr...

This tumour‑metabolism review interprets Rheb K8 ubiquitination as a molecular switch linking tumour‑microenvironment growth‑factor cues to mTORC1 signalling, RNF152‑USP4 regulatory axis, cell‑line‑xenograft‑AOM‑DSS in‑vivo experimental outputs and targeted‑small‑molecule research prospects. It...

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Ubiquitination and Neurodegeneration: The Hijacking‑Sequestration Model Explains Pathogenic Mechanisms Behind Pathological Protein Aggregation

Ubiquitination and Neurodegeneration: The Hijacking‑Sequestration Model Expla...

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This neuro‑biology review explains the “hijacking‑sequestration model” for ubiquitin‑driven neurodegenerative pathogenesis, polyQ‑disease molecular mechanisms, shared pathological features of inclusion‑bodies in Alzheimer’s and Parkinson’s disease, and atypical SdeA‑mediated ubiquitination biochemistry. It...

19 Aug 2026AntBio

Ubiquitination and Neurodegeneration: The Hijacking‑Sequestration Model Expla...

This neuro‑biology review explains the “hijacking‑sequestration model” for ubiquitin‑driven neurodegenerative pathogenesis, polyQ‑disease molecular mechanisms, shared pathological features of inclusion‑bodies in Alzheimer’s and Parkinson’s disease, and atypical SdeA‑mediated ubiquitination biochemistry. It...

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