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Invivo anti-Mouse IL-2 Recombinant mAb

Invivo anti-Mouse IL-2 Recombinant mAb

Catalog Number: S0B7155 Application: WB, in vivo neutralization Reactivity: Ms Conjugation: Unconjugated Brand: Starter
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Regular price $175 USD
Regular price Sale price $175 USD
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Product Details

Product Specification


Host Rat
Antigen IL-2
Synonyms Interleukin-2; T-cell growth factor (TCGF); Il-2; Il2
Location Secreted
Accession P04351
Clone Number S-5581
Antibody Type Rat mAb
Isotype Rat IgG2a, κ
Isotype Control S0B0932
Application WB, in vivo neutralization
Reactivity Ms
Purification Protein G
Concentration 5 mg/ml
Purity >95% (Determined by SDS-PAGE)
Endotoxin <1EU/mg
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, containing no preservative

Stability & Storage

2 to 8 °C for 2 weeks under sterile conditions;
-20 °C for 3 months under sterile conditions;
-80 °C for 24 months under sterile conditions.
Please avoid repeated freeze-thaw cycles.

Dilution


application dilution species
WB 1:1000 Ms

Background

Interleukin-2 (IL-2) is a cytokine that plays a crucial role in the immune system. It is primarily produced by activated T cells and has multiple functions. IL-2 promotes the proliferation and differentiation of T cells, enhancing their ability to fight infections and tumors. It also stimulates the growth and activity of natural killer (NK) cells, which are important for immune defense. Additionally, IL-2 can regulate the activity of regulatory T cells (Tregs), helping to maintain immune tolerance and prevent autoimmune diseases. In clinical settings, IL-2 has been used to treat certain cancers by boosting the immune response, although its use is limited due to potential side effects. Its discovery and research have significantly advanced our understanding of the immune system and provided new strategies for immunotherapy.

Picture

Western Blot

WB result of Invivo anti-Mouse IL-2 Recombinant mAb
Primary antibody: Invivo anti-Mouse IL-2 Recombinant mAb at 1/1000 dilution
Lane 1: IL-2 Protein, Mouse lysate 1 µg
Lane 2: IL-2 Protein, Rat lysate 1 µg
Lane 3: IL-2 Protein, Human lysate 1 µg
Secondary antibody: Goat Anti-Rat IgG (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 18 kDa
Observed MW: 18 kDa