Recent Articles
How Atypical PKCζ Regulates Path...
Roles of Serine/Threonine Phosph...
Histone Crotonylation: Reshaping...
Targeting the Notch1-Jagged1/NF-κB(p65) pathway: Can bruceine D inhibit tumor...
1. How does the "tumor-CAF-inflammation" malignant network in the tumor microenvironment drive TNBC metastasis? Triple-negative breast cancer (TNBC) is highly aggressive, prone to distant metastasis, and has an extremely poor...
Targeting the Notch1-Jagged1/NF-κB(p65) pathway: Can bruceine D inhibit tumor...
1. How does the "tumor-CAF-inflammation" malignant network in the tumor microenvironment drive TNBC metastasis? Triple-negative breast cancer (TNBC) is highly aggressive, prone to distant metastasis, and has an extremely poor...
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Can activating NRF2 (Ser40) be a key strategy for intervening in ferroptosis ...
1. How does the NRF2 signaling pathway regulate cellular ferroptosis defense mechanisms? Ferroptosis is an iron-dependent, lipid peroxidation-driven novel form of programmed cell death characterized by the loss of glutathione...
Can activating NRF2 (Ser40) be a key strategy for intervening in ferroptosis ...
1. How does the NRF2 signaling pathway regulate cellular ferroptosis defense mechanisms? Ferroptosis is an iron-dependent, lipid peroxidation-driven novel form of programmed cell death characterized by the loss of glutathione...
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How does the phosphorylation status of PLCγ1 (Tyr783) regulate phase separati...
1. What is the formation and regulatory mechanism of immune receptor signaling microclusters? When immune cells are activated, receptors on the cell surface (such as TCR, BCR, CAR, etc.) and...
How does the phosphorylation status of PLCγ1 (Tyr783) regulate phase separati...
1. What is the formation and regulatory mechanism of immune receptor signaling microclusters? When immune cells are activated, receptors on the cell surface (such as TCR, BCR, CAR, etc.) and...
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How does the regulatory state of PRAS40 (Thr246) affect the progression and p...
1. What role does PRAS40 play in the mTOR signaling pathway? PRAS40 (Proline-rich Akt substrate of 40 kDa) is a key regulatory factor in the mammalian target of rapamycin (mTOR)...
How does the regulatory state of PRAS40 (Thr246) affect the progression and p...
1. What role does PRAS40 play in the mTOR signaling pathway? PRAS40 (Proline-rich Akt substrate of 40 kDa) is a key regulatory factor in the mammalian target of rapamycin (mTOR)...
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How does tyrosine phosphorylation of nuclear PTEN regulate the radiosensitivi...
1. Is PTEN's function in tumors limited to the classical PI3K/AKT pathway inhibition? PTEN, as a key tumor suppressor, is widely recognized for its classical function of inhibiting cell proliferation...
How does tyrosine phosphorylation of nuclear PTEN regulate the radiosensitivi...
1. Is PTEN's function in tumors limited to the classical PI3K/AKT pathway inhibition? PTEN, as a key tumor suppressor, is widely recognized for its classical function of inhibiting cell proliferation...
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What are the regulatory mechanisms and functions of RIPK1 kinase activity (Se...
1. What role does Rab10 play in G protein-coupled receptor trafficking? G protein-coupled receptors (GPCRs) are one of the most important transmembrane receptor families on the cell surface, involved in...
What are the regulatory mechanisms and functions of RIPK1 kinase activity (Se...
1. What role does Rab10 play in G protein-coupled receptor trafficking? G protein-coupled receptors (GPCRs) are one of the most important transmembrane receptor families on the cell surface, involved in...
Read More