{"product_id":"mouse-mdscs-panel-kit-cd11bgr-1ly6cly6gcd115-s0n0018","title":"Mouse MDSCs Panel Kit (CD11b\/GR-1\/LY6C\/LY6G\/CD115)","description":"\u003ch4\u003eProduct Specification\u003c\/h4\u003e\u003cdiv class=\"responsive-table product-detail-table details-table\"\u003e\n\u003cbr\u003e\u003ctable style=\"width: 100%; height: auto;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eApplication\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eFCM\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eReactivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eMs\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003ePositive Sample\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eMouse bone marrow, Mouse splenocytes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003ePhysical Appearance\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eLiquid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eStorage Buffer\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u003cp\u003ePBS, 1% BSA, 0.09% sodium azide\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eStability \u0026amp; Storage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u003cp\u003e12 months from date of receipt \/ reconstitution, 2 to 8 °C as supplied.\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cdiv\u003e\u003cp\u003e\u003cspan\u003eThis five\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003ecolor panel is designed for detecting myeloid\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003ederived suppressor cell (MDSC) subsets in mouse\u003c\/span\u003e\u003cspan\u003e tissue cells\u003c\/span\u003e\u003cspan\u003e. CD11b was included as a general myeloid cell marker, and Ly\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003e6G\/Ly\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003e6C (Gr\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003e1) was included to identify the total myeloid population . Ly6C and Ly6G were then used to distinguish monocytic MDSCs (M\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003eMDSC) and granulocytic MDSCs (G\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003eMDSC). Finally, CD115 (the M\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003eCSF receptor) was included to further characterize myeloid cells, as its expression can provide additional information on monocyte\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003erelated populations or MDSC differentiation stages. The panel is compatible with most t\u003c\/span\u003e\u003cspan\u003ewo\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003elaser flow cytometers. If desired, the panel can serve as a backbone panel, allowing for the addition of antibodies conjugated to various fluorophores to detect other markers of interest.\u003c\/span\u003e\u003c\/p\u003e\u003c\/div\u003e","brand":"Starter","offers":[{"title":"50T","offer_id":42968334860363,"sku":"S0N0018-50T","price":310.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/8375\/1499\/files\/AntBioImage_141dcd86-edac-471a-af19-8554bed8c742.png?v=1785726016","url":"https:\/\/www.antbioinc.com\/products\/mouse-mdscs-panel-kit-cd11bgr-1ly6cly6gcd115-s0n0018","provider":"AntBio","version":"1.0","type":"link"}