{"product_id":"monkey-e-selectincd62e-onestep-elisa-kit-s0c3208","title":"Monkey E-Selectin\/CD62E OneStep ELISA Kit","description":"\u003ch4\u003eProduct Specification\u003c\/h4\u003e\u003cdiv class=\"responsive-table product-detail-table details-table\"\u003e\n\u003cbr\u003e\u003ctable style=\"width: 100%; height: auto;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eAntigen\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eMonkey E-selectin\/CD62E\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eImmunogen\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eRecombinant Protein\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eAntibody Type\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eRecombinant mAb\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eReactivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eMk\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eCross Reactivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u003cp\u003eHu\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003ePurification\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eProtein A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eStability \u0026amp; Storage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u003cp\u003e12 months from date of receipt \/ reconstitution, 2 to 8°C as supplied.\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003ch4\u003eKit\u003c\/h4\u003e\u003cdiv class=\"responsive-table product-detail-table details-table\"\u003e\n\u003cbr\u003e\u003ctable style=\"width: 100%; height: auto;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003ePrecision\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eIntra-assay: 3.9%；\u003cbr\u003eInter-assay: 4.1%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eSample type\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eSerum; Heparin Plasma, Citrate Plasma; Cell Culture Supernatant\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eAssay type\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eSandwich (quantitative)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eSensitivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e9.75 pg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eRange\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e23.44 pg\/mL – 1500 pg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eRecovery\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eSerum: 101%\u003cbr\u003eCitrate plasma: 93%\u003cbr\u003eHeparin Plasma: 94%\u003cbr\u003eCell Culture Supernatant: 112%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eAssay time\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e60 minutes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eSpecies reactivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eMk\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eCROSS REACTIVITY\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eHu\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cdiv\u003e\u003cp\u003e\u003cspan style=\"color:#0F1115\"\u003eMonkey E-selectin (CD62E, ELAM-1) is a 107–115 kDa type I transmembrane glycoprotein of the selectin family, structurally composed of an extracellular C-type lectin domain (responsible for calcium-dependent carbohydrate recognition), an EGF-like domain, and six short consensus repeats, followed by a transmembrane region and a short cytoplasmic tail. Cynomolgus monkey E-selectin shares \u003c\/span\u003e\u003cspan style=\"font-weight:bold;color:#0F1115\"\u003e96% amino acid identity\u003c\/span\u003e\u003cspan style=\"color:#0F1115\"\u003e with human E-selectin, making it a highly relevant translational model. E-selectin is expressed \u003c\/span\u003e\u003cspan style=\"font-weight:bold;color:#0F1115\"\u003eexclusively on activated endothelial cells\u003c\/span\u003e\u003cspan style=\"color:#0F1115\"\u003e, with peak induction at approximately 4 hours after stimulation by pro-inflammatory cytokines (TNF-α, IL-1β), followed by rapid decline within 24 hours. It mediates the initial tethering and rolling of leukocytes (neutrophils, monocytes, memory T cells) along the vascular endothelium by binding to sialylated\/fucosylated ligands such as \u003c\/span\u003e\u003cspan style=\"font-weight:bold;color:#0F1115\"\u003eSialyl Lewis X (CD15s)\u003c\/span\u003e\u003cspan style=\"color:#0F1115\"\u003e and \u003c\/span\u003e\u003cspan style=\"font-weight:bold;color:#0F1115\"\u003ePSGL-1 (CD162).\u003c\/span\u003e\u003cspan style=\"color:#0F1115\"\u003e Key binding residues identified by crystallography (PDB 1g1t) include Y48, N82, N83, E92, Y94, R97, N105, E107, E80, E98, and D106. After peak expression, E-selectin is proteolytically cleaved into \u003c\/span\u003e\u003cspan style=\"font-weight:bold;color:#0F1115\"\u003esoluble E-selectin\u003c\/span\u003e\u003cspan style=\"color:#0F1115\"\u003e, which circulates in blood and serves as a biomarker of endothelial activation.\u003c\/span\u003e\u003c\/p\u003e\u003c\/div\u003e","brand":"Starter","offers":[{"title":"1x96T","offer_id":43068429434955,"sku":"S0C3208-1x96T","price":670.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/8375\/1499\/files\/7938c07308f2410582f8f8650f4ff18e.jpg?v=1787630798","url":"https:\/\/www.antbioinc.com\/products\/monkey-e-selectincd62e-onestep-elisa-kit-s0c3208","provider":"AntBio","version":"1.0","type":"link"}