{"product_id":"human-mlr-panel-kit-s0n0010","title":"Human MLR Panel Kit","description":"\u003ch4\u003eProduct Specification\u003c\/h4\u003e\u003cdiv class=\"responsive-table product-detail-table details-table\"\u003e\n\u003cbr\u003e\u003ctable style=\"width: 100%; height: auto;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eApplication\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eFCM\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eReactivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eHu\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003ePhysical Appearance\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eLiquid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eStorage Buffer\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u003cp\u003ePBS, 1% BSA, 0.09% sodium azide\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eStability \u0026amp; Storage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u003cp\u003e12 months from date of receipt \/ reconstitution, 2 to 8 °C as supplied.\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cdiv\u003e\u003cp\u003e\u003cspan\u003eThis five\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003ecolor panel is designed for evaluating dendritic cell (DC) maturation and activation status \u003c\/span\u003e\u003cspan style=\"color:#0F1115\"\u003ein human peripheral blood or other biological samples\u003c\/span\u003e\u003cspan\u003e. CD3 was included as a T\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003ecell marker to gate\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eout\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eT lymphocytes, ensuring that the analysis focuses on the CD3\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003enegative population. HLA\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003eDR and CD11c were included to identify conventional dendritic cells (\u003c\/span\u003e\u003cspan\u003ecDCs\u003c\/span\u003e\u003cspan\u003e) . Finally, the expression of CD80 and CD86 on the gated \u003c\/span\u003e\u003cspan\u003ecDC\u003c\/span\u003e\u003cspan\u003e population is indicative of DC maturation and activation; positivity for either marker reflects an activated state, and combined expression can further distinguish mature DC subsets. The panel is compatible with most two\u003c\/span\u003e\u003cspan\u003e‑\u003c\/span\u003e\u003cspan\u003elaser flow cytometers. If desired, the panel can serve as a backbone panel, allowing for the addition of antibodies conjugated to various fluorophores to detect other markers of interest, for more detailed functional characterization.\u003c\/span\u003e\u003c\/p\u003e\u003c\/div\u003e","brand":"Starter","offers":[{"title":"50T","offer_id":43095294148683,"sku":"S0N0010-50T","price":666.67,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/8375\/1499\/files\/103f5b2f41e448f98c58c0b717a90c56.jpg?v=1788213838","url":"https:\/\/www.antbioinc.com\/products\/human-mlr-panel-kit-s0n0010","provider":"AntBio","version":"1.0","type":"link"}