{"product_id":"human-b-cell-panel-kit-s0n0004","title":"Human B Cell Panel Kit","description":"\u003ch4\u003eProduct Specification\u003c\/h4\u003e\u003cdiv class=\"responsive-table product-detail-table details-table\"\u003e\n\u003cbr\u003e\u003ctable style=\"width: 100%; height: auto;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eApplication\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eFCM\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eReactivity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eHu\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003ePhysical Appearance\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eLiquid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eStorage Buffer\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u003cp\u003ePBS, 1% BSA, 0.09% sodium azide\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eStability \u0026amp; Storage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u003cp\u003e12 months from date of receipt \/ reconstitution, 2 to 8 °C as supplied.\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cdiv\u003e\u003cp\u003e\u003cspan\u003eThis five‑color panel is designed for characterizing B‑cell subsets and plasma cells in human peripheral blood or other biological samples, with a focus on differentiation stages from immature to mature B lymphocytes and terminally differentiated antibody‑secreting cells. CD19 was included as a pan‑B‑cell marker to identify the total B‑cell population, and CD20 was included to distinguish mature B cells from plasma cells, as CD20 is downregulated upon terminal differentiation. CD138 is a marker often used to detect plasma cells; when combined with CD38, which is highly expressed on activated B cells and plasmablasts, the panel allows the discrimination of plasma cells, activated B cells\/plasmablasts, and resting mature B cells. Furthermore, the expression pattern of CD38 and CD24 on B cells can identify transitional B cells, plasmablasts, and resting mature B cells. The panel is compatible with most standard three‑laser flow cytometers. If desired, the panel can serve as a backbone B‑cell tube, allowing for the addition of antibodies conjugated to various fluorophores to detect other markers of interest for more refined subsetting.\u003c\/span\u003e\u003c\/p\u003e\u003c\/div\u003e","brand":"Starter","offers":[{"title":"50T","offer_id":43095293263947,"sku":"S0N0004-50T","price":666.67,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/8375\/1499\/files\/568f369b3ba6464ea5316a899b7c8a58.jpg?v=1788213823","url":"https:\/\/www.antbioinc.com\/products\/human-b-cell-panel-kit-s0n0004","provider":"AntBio","version":"1.0","type":"link"}