{"product_id":"bmp-2-protein-humanmouserat-ua040572","title":"BMP-2 Protein, Human\/Mouse\/Rat","description":"\u003ch4\u003eProduct Specification\u003c\/h4\u003e\u003cdiv class=\"responsive-table product-detail-table details-table\"\u003e\n\u003cbr\u003e\u003ctable style=\"width: 100%; height: auto;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eBone morphogenetic protein 2, BMP-2, Bone morphogenetic protein 2A (BMP-2A)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eAccession\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eP12643\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eAmino Acid Sequence\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u003cp\u003eLeu284-Arg396\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eExpression System\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eCHO\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u003cp style=\"margin-bottom: 0px;\"\u003e14-16 kDa (Reducing)\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u0026gt;95% by SDS-PAGE.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eEndotoxin\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eConjugation\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eUnconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eTag\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eNo Tag\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003ePhysical Appearance\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003eLyophilized Powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eStorage Buffer\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u003cp\u003e4mM HCl\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eReconstitution\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u003cp\u003e\u003cspan\u003eReconstitute at 0.1-1 mg\/ml according to the size in Reconstitution Buffer after rapid centrifugation.\u003c\/span\u003e\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eStability \u0026amp; Storage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u003cp\u003e\u003cspan\u003e·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e·3 months, -20 to -80℃ under sterile conditions after reconstitution.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e·1 week, 2 to 8℃ under sterile conditions after reconstitution.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e·Please avoid repeated freeze-thaw cycles.\u003c\/span\u003e\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eReference\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 78%;\"\u003e\u003cp\u003eBone: formation by autoinduction. Science 150, 893–899 (1965).\u003cbr\u003eNovel regulators of bone formation: molecular clones and activities. Science 242, 1528–1534 (1988).\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003c\/div\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cspan\u003eBone morphogenetic protein 2 (BMP-2) is a multifunctional growth factor belonging to the transforming growth factor-β (TGF-β) superfamily. The osteoinductive activity of bone-derived proteins was first described by Marshall Urist in 1965. As one of the most potent osteoinductive factors known, BMP-2 initiates the differentiation of mesenchymal stem cells into osteoblasts and chondrocytes, playing essential roles in embryonic skeletal development, bone remodeling, and fracture healing.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIn the biomedical industry, rhBMP-2 received FDA approval in 2002 and is commercially available as the Infuse™ Bone Graft system, delivered via an absorbable collagen sponge carrier. Industrial applications are predominantly focused on spinal fusion surgeries, where rhBMP-2 has demonstrated fusion rates comparable to or higher than autologous bone grafts. Additional clinical indications include open tibial fractures, maxillofacial reconstruction, sinus augmentation, and treatment of femoral head necrosis. However, clinical use is constrained by dose-dependent complications including inflammation, ectopic ossification, osteolysis, and concerns regarding cost and safety.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"UA BIOSCIENCE","offers":[{"title":"10μg","offer_id":42887927070795,"sku":"UA040572-10μg","price":150.0,"currency_code":"USD","in_stock":true},{"title":"50μg","offer_id":42887927103563,"sku":"UA040572-50μg","price":375.0,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":42887927136331,"sku":"UA040572-100μg","price":600.0,"currency_code":"USD","in_stock":true},{"title":"500μg","offer_id":42887927169099,"sku":"UA040572-500μg","price":1800.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":42887927201867,"sku":"UA040572-1mg","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/8375\/1499\/files\/AntBioImage_25140ce0-6d17-42b6-9f11-d3fea6873592.png?v=1783774841","url":"https:\/\/www.antbioinc.com\/products\/bmp-2-protein-humanmouserat-ua040572","provider":"AntBio","version":"1.0","type":"link"}